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So the authors put clofibrate into the water of normal male mice, and mice that had the human TAS1R3 gene.

When these mice were given the drug clofibrate, which inhibits the human receptor, the males became sterile due to malformed and fewer sperm.

And if you got rid of the clofibrate?

The drug clofibrate that belongs to a class of chemicals called fibrates, which are frequently prescribed to treat lipid disorders, such as high blood cholesterol or high levels of triglycerides.

The mice quickly became fertile again once clofibrate was removed from their diet.