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Other procedures like laser depigmentation and iris implants have also been used to change the eye color, but may result in corneal damage or vision loss as well.

But it was an effective treatment for nonsegmental vitiligo - the most common type - where patches or blotches of depigmentation appear on both sides of the body.

Vitiligo is a common condition that causes depigmentation of the skin.

She sets high minimum quotas for female designers and once banned models using skin depigmentation cream to promote self-acceptance.

“By making that one small change in the protein, we were able to reverse the depigmentation process,” Le Poole says, adding that she was “shocked and awed by the result”.