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"Someone living with bipolar cannot be separated from it - their personality is entirely and intrinsically connected to the condition," says Prof Geddes.

Born in Chicago and raised in Aurora, Ill., Flores was intrinsically comical, deeply convinced that he was funnier than any of the booked comics he witnessed on stage.

It was astounding: complex, but with a salty, sharp note from the cheese that is so intrinsically cheese-y and couldn't be replicated with any other ingredient.

Some believe that it was intrinsically inept to target a benefit paid to pensioners.

Now in her second year as GM, Pebley is intrinsically linked to Roberts, with their roster-building synergy central to the team’s foundation.