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The Environmental Protection Agency does not consider it a carcinogen; however, exposure to barium can cause gastrointestinal irritation, cardiovascular effects, kidney damage and respiratory problems.

High-ventilation breathing is not recommended for people with epilepsy, lung diseases or asthma that limit breathing, high blood pressure or cardiovascular problems, and schizophrenia or a history of psychosis.

That difference at the cellular level is important, because women tend to have more salt-sensitive hypertension, a risk factor for cardiovascular disease, than men, especially in the menopausal phase.

Exercise in general has been shown to improve depression and reduce the risk of diabetes, cardiovascular disease and cancer.

It combines strength training, cardiovascular exercise and muscular endurance, with exercises performed at a very slow tempo, so muscles experience more time under tension.