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Identification and treatment of new and unremitting mood episodes is essential for limiting the impact of BD on patients' lives.

Their next step is to apply these predictive algorithms in routine care where they could be used to improve BD treatment by informing clinicians when their patients are experiencing depressive or manic episodes between scheduled appointments.

“Perhaps the most insidious result of inflating BD diagnoses, and the one which may be of most concern to social workers, is the masking of oppressive social conditions,” he writes.

“As a result,” Doyen writes, “there are serious concerns that the rise in BD diagnoses, with their biological underpinnings, is concealing increasing social and environmental distress among marginalized Americans.”

He and Aghdashloo have also made the performance itself a triumph, bringing a depth of emotion and strength of connection that were missing from this two-hander when I reviewed its first cast, BD Wong and Rosalind Chao.