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At the very least, this could force Israel to further attacks, potentially binding the region into a continual round of strike and counter-strike.

Waiting was found to have had a "catastrophic impact" on one patient's life who suffered daily pain, and another, awaiting an operation for bladder stones, endured "continual bleeding".

For the last five years, a loud hum has been a continual backdrop to birdsong and the occasional barking dog in the village of Dresden, New York state.

"I was really shocked at the levels of self-harm, the levels of violence, the lack of staff, the continual bang up," he said.

Nevertheless, she argues for ongoing research into nociception in invertebrates and continual adaptation of guidelines in response to what we learn.