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The road, both eastbound and westbound, remains closed as live cattle transferred to another lorry wait to be moved off site, as well as the overturned lorry.

The crash took place eastbound on the 210 Freeway, just west of State Route 2.

But the braking system failed on the eastbound train heading to Aberystwyth and it skidded past the loop, colliding with the westbound train from Machynlleth.

As of 5:40 p.m. the eastbound HOV lane was open on the freeway, but the remaining eastbound lanes were closed, according to the California Highway Patrol.

It is understood eastbound traffic can still use the road.