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second messenger
noun
any of various intracellular chemical substances, as cyclic AMP, that transmit and amplify the messages delivered by a first messenger to specific receptors on the cell surface.
second messenger
A molecule that relays messages in a cell from a receptor on a cell membrane to the final destination where an action within the cell is to take place. (See signal transduction pathway.)
51Թ History and Origins
Origin of second messenger1
Example Sentences
The latest data suggest Johnson & Johnson recipients should get a booster with one of the messenger RNA vaccines, if they haven’t already done so — and even consider a second messenger RNA booster for the greatest protection.
The entire circuit is modulated by the protein TCF7L2 that, acting through a second messenger molecule called cAMP, mediates the sensitivity of nAChR-expressing neurons to nicotine.
What’s more, Tiuri’s quest turns out to have been slightly redundant: A second messenger was wisely, if anti-dramatically, entrusted with the same message.
The first messenger’s arrival at the outer wall of the cell eventually causes production within the cell of a “second messenger,” which prompts the cell to act.
A second messenger announced that they had begun their march; our brazen drum was sounded, all were alert, the sultan came out, and I accompanied him: he surrounded them with chosen troops, and gave the signal for attack.”...
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