STATIN Definition & Meaning

statin

[stat-n]

Phonetic (Standard)IPA

noun

Pharmacology.

any of a class of drugs that reduce the levels of lipids in the blood by altering the enzyme activity in the liver that produces lipids: used in the prevention and treatment of heart disease.

statin

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noun

any of a class of drugs, including atorvastatin and simvastatin, that lower the levels of low-density lipoproteins in the blood by inhibiting the activity of an enzyme involved in the production of cholesterol in the liver

statin

Any of a class of drugs that inhibit a key enzyme involved in the synthesis of cholesterol and promote receptor binding of LDL-cholesterol, resulting in decreased levels of serum cholesterol and LDL-cholesterol and increased levels of HDL-cholesterol.

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51�Թ� History and Origins

Origin of statin¹

First recorded in 1985–90; extracted from (lova)statin and other drugs in this class

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Example Sentences

Examples have not been reviewed.

The decision ended one threat to the no-cost preventive services — from cancer and diabetes screenings to statin drugs and vaccines — used by more than 150 million Americans who have health insurance.

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Other drugs such as lithium or statins can become more concentrated and problematic in the blood if there is too much fluid loss.

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He said that when a new innovation came along, like statins did about 30 years ago, they were expensive at first - but then the price started to fall.

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For example, the study identified 156 genes that can potentially drive the variation of statins' impact on LDL cholesterol levels.

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Fortunately, this attention to cholesterol has prompted the development of cholesterol-lowering drugs called statins and lifestyle interventions like dietary and exercise regimens.

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